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polyclonal cmv igg  (CSL Behring)

 
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    Structured Review

    CSL Behring polyclonal cmv igg
    gB-specific mAbs mediate negligible NK activation ADCC responses when compared to <t>polyclonal</t> <t>CMV-specific</t> antibody preparation (Cytogam). gB-specific mAbs were screened for mediation of NK cell (A) CD107a degranulation and (B) CD16 downregulation (DRI) as measures of antibody-mediated NK cell activation. Data are presented as mAb specific response against AD169r-GFP infected ARPE19 cells minus mock infected negative control cells.
    Polyclonal Cmv Igg, supplied by CSL Behring, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/polyclonal+cmv+igg/polyclonal+cmv+igg+antibody/bio_rxiv__2020__01__14__907204-49-9-14
    Average 90 stars, based on 1 article reviews
    polyclonal cmv igg - by Bioz Stars, 2026-10
    90/100 stars

    Images

    1) Product Images from "Specificity and effector functions of non-neutralizing gB-specific monoclonal antibodies isolated from healthy individuals with human cytomegalovirus infection"

    Article Title: Specificity and effector functions of non-neutralizing gB-specific monoclonal antibodies isolated from healthy individuals with human cytomegalovirus infection

    Journal: bioRxiv

    doi: 10.1101/2020.01.14.907204

    gB-specific mAbs mediate negligible NK activation ADCC responses when compared to polyclonal CMV-specific antibody preparation (Cytogam). gB-specific mAbs were screened for mediation of NK cell (A) CD107a degranulation and (B) CD16 downregulation (DRI) as measures of antibody-mediated NK cell activation. Data are presented as mAb specific response against AD169r-GFP infected ARPE19 cells minus mock infected negative control cells.
    Figure Legend Snippet: gB-specific mAbs mediate negligible NK activation ADCC responses when compared to polyclonal CMV-specific antibody preparation (Cytogam). gB-specific mAbs were screened for mediation of NK cell (A) CD107a degranulation and (B) CD16 downregulation (DRI) as measures of antibody-mediated NK cell activation. Data are presented as mAb specific response against AD169r-GFP infected ARPE19 cells minus mock infected negative control cells.

    Techniques Used: Activation Assay, Infection, Negative Control

    Related Articles

    Western Blot:

    Article Title: Specificity and effector functions of non-neutralizing gB-specific monoclonal antibodies isolated from healthy individuals with human cytomegalovirus infection
    Article Snippet: Supernatant was harvested 5 days later, and purified using Nickel-NTA resin for gB Domain II (Thermo Fisher Scientific), and lectin resin (VWR) for gB Domain I. .. Purity and identity were confirmed by Western blot using polyclonal CMV IgG (Cytogam – CSL Behring) or monoclonal antibodies SM10 (Domain I) and SM5-1 (Domain II). ..

    Bioprocessing:

    Article Title: Specificity and effector functions of non-neutralizing gB-specific monoclonal antibodies isolated from healthy individuals with human cytomegalovirus infection
    Article Snippet: Supernatant was harvested 5 days later, and purified using Nickel-NTA resin for gB Domain II (Thermo Fisher Scientific), and lectin resin (VWR) for gB Domain I. .. Purity and identity were confirmed by Western blot using polyclonal CMV IgG (Cytogam – CSL Behring) or monoclonal antibodies SM10 (Domain I) and SM5-1 (Domain II). ..



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    Image Search Results


    gB-specific mAbs mediate negligible NK activation ADCC responses when compared to polyclonal CMV-specific antibody preparation (Cytogam). gB-specific mAbs were screened for mediation of NK cell (A) CD107a degranulation and (B) CD16 downregulation (DRI) as measures of antibody-mediated NK cell activation. Data are presented as mAb specific response against AD169r-GFP infected ARPE19 cells minus mock infected negative control cells.

    Journal: bioRxiv

    Article Title: Specificity and effector functions of non-neutralizing gB-specific monoclonal antibodies isolated from healthy individuals with human cytomegalovirus infection

    doi: 10.1101/2020.01.14.907204

    Figure Lengend Snippet: gB-specific mAbs mediate negligible NK activation ADCC responses when compared to polyclonal CMV-specific antibody preparation (Cytogam). gB-specific mAbs were screened for mediation of NK cell (A) CD107a degranulation and (B) CD16 downregulation (DRI) as measures of antibody-mediated NK cell activation. Data are presented as mAb specific response against AD169r-GFP infected ARPE19 cells minus mock infected negative control cells.

    Article Snippet: Purity and identity were confirmed by Western blot using polyclonal CMV IgG (Cytogam – CSL Behring) or monoclonal antibodies SM10 (Domain I) and SM5-1 (Domain II).

    Techniques: Activation Assay, Infection, Negative Control